Pre_GI Gene

Some Help

Host: NC_003155 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003155:3913789 Streptomyces avermitilis MA-4680, complete genome

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
39137893914658870DNA-binding proteinQuickGO ontologyBLASTP
39146553914867213hypothetical proteinBLASTP
39149783915172195secreted proteinQuickGO ontologyBLASTP
391536039174922133peptidaseQuickGO ontologyBLASTP
391764239187271086peptide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
39187203919703984peptide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
39197113920631921oligopeptide ABC transporter integral membrane proteinQuickGO ontologyBLASTP
39206813921604924oligopeptide ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
392165939232811623oligopeptide ABC transporter substrate-binding proteinQuickGO ontologyBLASTP
39237763924765990ABC transporter integral membrane protein BldKAQuickGO ontologyBLASTP
392484739266101764ABC transporter protein BldKBQuickGO ontologyBLASTP
39267363927716981ABC transporter integral membrane protein BldKCQuickGO ontologyBLASTP
392777739288471071ABC transporter intracellular ATPase BldKDQuickGO ontologyBLASTP
392887139299171047ABC transporter ATP-binding protein BldKEQuickGO ontologyBLASTP
39300883930255168MbtH-like proteinQuickGO ontologyBLASTP
393030639321831878non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
393226139335531293export proteinQuickGO ontologyBLASTP
39336133934425813non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
393443939374893051non-ribosomal peptide synthetaseQuickGO ontologyBLASTP