Pre_GI: BLASTP Hits

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Query: NC_002945:3073370:3093191 Mycobacterium bovis AF2122/97, complete genome

Start: 3093191, End: 3093583, Length: 393

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_012207:3063039:308337930833793083771393Mycobacterium bovis BCG str. Tokyo 172, complete genomehypothetical protein2e-68257
NC_019950:3139865:315970231597023160094393Mycobacterium canettii CIPT 140060008 complete genomeConserved protein of unknown function with PIN domain, possible toxin VapC225e-62235
NC_015848:3175692:319531931953193195711393Mycobacterium canettii CIPT 140010059, complete genomehypothetical protein5e-62235
NC_015726:3452232:345761534576153458010396Cupriavidus necator N-1 chromosome 1, complete sequenceprotein PilT5e-1579.7
NC_007514:904565:933737933737934126390Chlorobium chlorochromatii CaD3, complete genomehypothetical protein5e-1373.2
NC_010475:420978:430718430718431107390Synechococcus sp. PCC 7002, complete genomeconserved hypothetical protein, PIN domain1e-1168.2
NC_005125:3981987:400584740058474006272426Gloeobacter violaceus PCC 7421, complete genomehypothetical protein5e-0856.6
NC_013946:2050871:207096720709672071377411Meiothermus ruber DSM 1279 chromosome, complete genomePilT domain-containing protein7e-0856.2