Pre_GI Gene

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Host: NC_017516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017516:1439775 Neisseria meningitidis H44/76 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
14397751440077303ATP-dependent Clp protease adaptor protein ClpSQuickGO ontologyBLASTP
144007914423882310ATP-dependent Clp protease ATP-binding subunit ClpAQuickGO ontologyBLASTP
14452681446233966transposase IS30 familyQuickGO ontologyBLASTP
144660514477471143hypothetical proteinBLASTP
144913214501421011hypothetical proteinBLASTP
145013914516801542type I restriction-modification system M subunitQuickGO ontologyBLASTP
145175714527611005ADP-glyceromanno-heptose 6-epimeraseQuickGO ontologyBLASTP
145289014539211032hypothetical proteinBLASTP
145392314551431221DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
14551951456166972hldE bifunctional protein domain IQuickGO ontologyBLASTP
14562211456961741orotidine 5-phosphate decarboxylaseQuickGO ontologyBLASTP
14574871458134648adenylate kinaseQuickGO ontologyBLASTP
14583501459189840peptidase M48 familyQuickGO ontologyBLASTP
14594901460050561hypothetical proteinBLASTP
14601641460556393NUMOD1 domain proteinQuickGO ontologyBLASTP
14607641461168405hypothetical proteinBLASTP
14612731461683411hypothetical proteinBLASTP
14616971462134438hypothetical proteinBLASTP
14621061462426321hypothetical proteinBLASTP