Pre_GI Gene

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Host: NC_017513 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017513:9081 Neisseria meningitidis G2136 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
908110055975protein AlxQuickGO ontologyBLASTP
1008810537450hypothetical proteinBLASTP
105781184912723-deoxy-D-manno-octulosonic-acid transferaseQuickGO ontologyBLASTP
119121336014496-phosphogluconate dehydrogenaseQuickGO ontologyBLASTP
1472215678957putative transposaseQuickGO ontologyBLASTP
15893170801188hypothetical proteinBLASTP
17668189631296Neisseria meningitidis TspB family proteinQuickGO ontologyBLASTP
1962819930303hypothetical proteinBLASTP
1995820188231hypothetical proteinBLASTP
2042620626201hypothetical proteinBLASTP
2063020941312hypothetical proteinBLASTP
2095321678726Replication initiation factor family proteinQuickGO ontologyBLASTP
2279323716924UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deacetylaseQuickGO ontologyBLASTP
2487325160288fimbrial protein P9-2 precursorQuickGO ontologyBLASTP
2518625620435fimbrial protein MS11-D1 precursorQuickGO ontologyBLASTP
2566726029363fimbrial proteinQuickGO ontologyBLASTP
2605826387330FKBP-type peptidyl-prolyl cis-trans isomeraseQuickGO ontologyBLASTP
2695927912954glycerate dehydrogenaseQuickGO ontologyBLASTP
27990300442055methionyl-tRNA synthetaseQuickGO ontologyBLASTP