Pre_GI Gene

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Host: NC_017316 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017316:1840462 Enterococcus faecalis OG1RF chromosome, complete genome

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
184046218421921731sensor histidine kinaseQuickGO ontologyBLASTP
18421461842781636hypothetical protein
184285218443181467ABC superfamily ATP binding cassette transporter binding proteinQuickGO ontologyBLASTP
18443421845265924carbohydrate ABC superfamily ATP binding cassette transporter membrane proteinQuickGO ontologyBLASTP
18452771846233957ABC superfamily ATP binding cassette transporter membrane proteinQuickGO ontologyBLASTP
184677218524685697cell wall surface anchor family proteinQuickGO ontologyBLASTP
18529421853757816MerR family transcriptional regulatorQuickGO ontologyBLASTP
185382418555511728multidrug ABC superfamily ATP binding cassette transporter ABC proteinQuickGO ontologyBLASTP
185560418573821779ABC superfamily ATP binding cassette transporter membrane proteinQuickGO ontologyBLASTP
185743618584401005tryptophan--tRNA ligaseQuickGO ontologyBLASTP
185860218623813780hypothetical proteinBLASTP