Pre_GI Gene

Some Help

Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:678582 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6785826803121731dihydroxyacetone kinaseQuickGO ontologyBLASTP
680303680806504phosphoribosyl transferase domain proteinQuickGO ontologyBLASTP
680896681396501GNAT family acetyltransferaseQuickGO ontologyBLASTP
6817606833071548NADP transhydrogenase subunit alphaQuickGO ontologyBLASTP
6833116847321422NADP transhydrogenase subunit betaQuickGO ontologyBLASTP
684878685198321ferredoxin family proteinQuickGO ontologyBLASTP
6851956862981104N-succinyldiaminopimelate aminotransferaseQuickGO ontologyBLASTP
686299687141843lipoproteinQuickGO ontologyBLASTP
6872396882019632345-tetrahydropyridine-26-dicarboxylate N-succinyltransferaseQuickGO ontologyBLASTP
6885826897121131glycine amidinotransferaseQuickGO ontologyBLASTP
6898366908971062hypothetical proteinBLASTP
6909136922081296prolinebetaine transporterQuickGO ontologyBLASTP
692221692712492transcriptional regulator TetR family proteinQuickGO ontologyBLASTP
6929536940321080succinyl-diaminopimelate desuccinylaseQuickGO ontologyBLASTP
694077694382306DivIVA domain-containing proteinQuickGO ontologyBLASTP
694423694590168hypothetical proteinBLASTP
6946546958381185glycogen synthaseQuickGO ontologyBLASTP
6959826972081227glucose-1-phosphate adenylyltransferaseQuickGO ontologyBLASTP
697291697944654O-methyltransferaseQuickGO ontologyBLASTP
698014698895882dihydrodipicolinate synthaseQuickGO ontologyBLASTP
698946699359414sec-independent translocaseQuickGO ontologyBLASTP
6995127010861575endoglycoceramidaseQuickGO ontologyBLASTP
7011427023021161mrp family proteinQuickGO ontologyBLASTP