Pre_GI Gene

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Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:234431 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
234225234434210hypothetical protein
234431235024594hypothetical proteinBLASTP
2351422362841143hypothetical proteinBLASTP
2362272402974071YD repeat proteinQuickGO ontologyBLASTP
240398240580183hypothetical proteinBLASTP
240651241412762hypothetical proteinBLASTP
241786242685900hypothetical proteinBLASTP
243619244065447hypothetical proteinBLASTP
2450952475482454RHS repeat-associated core domain-containing proteinQuickGO ontologyBLASTP
250456251178723hypothetical proteinBLASTP
251548251913366S4 domain-containing proteinQuickGO ontologyBLASTP
252196252552357hypothetical proteinBLASTP
2526202554932874DNA polymerase III subunits gamma and tauQuickGO ontologyBLASTP
255601255924324DNA-binding protein YbaBEbfC familyQuickGO ontologyBLASTP
255955256560606recombination protein RecRQuickGO ontologyBLASTP
256668257243576transcriptional regulator PadR family proteinQuickGO ontologyBLASTP
257249258031783ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
2580282606702643efflux ABC transporter permeaseQuickGO ontologyBLASTP