Pre_GI Gene

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Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:260664 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2606642637593096CRISPR-associated Cas1 family proteinQuickGO ontologyBLASTP
263821264594774CRISPR-associated Cmr5 family proteinQuickGO ontologyBLASTP
264591265028438hypothetical proteinBLASTP
265025265726702CRISPR-associated Cmr4 family proteinQuickGO ontologyBLASTP
2657402669511212CRISPR-associated Cmr3 family proteinQuickGO ontologyBLASTP
2669532686021650CRISPR-associated Csm1 family proteinQuickGO ontologyBLASTP
2685952700461452hypothetical proteinBLASTP
270053270304252hypothetical proteinBLASTP
2703062718891584hypothetical proteinBLASTP
272195272392198hypothetical proteinBLASTP
2726312745081878tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidAQuickGO ontologyBLASTP
2745392763411803excinuclease ABC C subunitQuickGO ontologyBLASTP
276348276800453D-tyrosyl-tRNATyr deacylaseQuickGO ontologyBLASTP
276805277155351hypothetical proteinBLASTP
277142278011870deoxyribose-phosphate aldolaseQuickGO ontologyBLASTP
278052278213162hypothetical proteinBLASTP
278322279296975putative polyprenyl synthetaseQuickGO ontologyBLASTP
279354279992639hypothetical proteinBLASTP