Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:3288500 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
32886213288821201cold shock proteinQuickGO ontologyBLASTP
32890383289937900hypothetical proteinBLASTP
32899543290397444flavodoxinQuickGO ontologyBLASTP
32905153291159645GPR1FUN34YaaH family proteinQuickGO ontologyBLASTP
32912453291640396MutTNudix family proteinQuickGO ontologyBLASTP
32916373291978342hypothetical proteinBLASTP
32920893292646558acetyltransferaseQuickGO ontologyBLASTP
329269432999327239hypothetical proteinBLASTP
33002833301032750short-chain dehydrogenasereductase family oxidoreductaseQuickGO ontologyBLASTP
33010683301901834acetyltransferase GNAT familyQuickGO ontologyBLASTP
330196833034761509argininosuccinate lyaseQuickGO ontologyBLASTP
330357833046181041hypothetical proteinBLASTP
330480433058081005inosine-uridine preferring nucleoside hydrolaseQuickGO ontologyBLASTP
330585333072921440sodiumpantothenate symporterQuickGO ontologyBLASTP