Pre_GI: BLASTP Hits

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Query: NC_014335:3288500:3301068 Bacillus cereus biovar anthracis str. CI chromosome, complete

Start: 3301068, End: 3301901, Length: 834

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011773:3371989:339121633912163392049834Bacillus cereus AH820 chromosome, complete genomeGNAT family acetyltransferase1e-153542
NC_018704:1424728:142625714262571427123867Amphibacillus xylanus NBRC 15112, complete genomeputative acetyltransferase1e-32140
NC_007777:2186000:218714121871412188004864Frankia sp. CcI3, complete genomeGCN5-related N-acetyltransferase1e-1790.5
NC_013595:5282207:530740253074025308289888Streptosporangium roseum DSM 43021, complete genomeacetyltransferase-like protein6e-1271.6