Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:5015621 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
50156215016301681hypothetical proteinBLASTP
50163185017016699hypothetical proteinBLASTP
501713050183381209ABC transporter permease componentQuickGO ontologyBLASTP
50183265019006681ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
501900350201961194efflux transporter RND family MFP subunitQuickGO ontologyBLASTP
50205705020761192DNA-binding proteinQuickGO ontologyBLASTP
50207625021274513hypothetical proteinBLASTP
502137950227131335phosphoglycerate transporter family proteinQuickGO ontologyBLASTP
502273350237671035putative lipoproteinQuickGO ontologyBLASTP
50237645024546783hypothetical proteinBLASTP
502461350260431431sensor histidine kinaseQuickGO ontologyBLASTP
50260555026726672DNA-binding response regulatorQuickGO ontologyBLASTP
50268495027793945mannose-6-phosphate isomerase class IQuickGO ontologyBLASTP
502781150297631953phosphotransferase systemQuickGO ontologyBLASTP
502990750318531947transcriptional regulatorQuickGO ontologyBLASTP
50320345033026993UDP-glucose 4-epimeraseQuickGO ontologyBLASTP
50331165033934819epsx proteinQuickGO ontologyBLASTP
50340345034948915membrane-bound protein LytRQuickGO ontologyBLASTP
50350605036007948mannose-6-phosphate isomerase class IQuickGO ontologyBLASTP
503604450374171374mannose-1-phosphate guanylyltransferaseQuickGO ontologyBLASTP
503743550386311197glycosyltransferase group 1 family proteinQuickGO ontologyBLASTP