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Query: NC_012472:5015621:5016318 Bacillus cereus 03BB102, complete genome

Start: 5016318, End: 5017016, Length: 699

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008600:5005345:500604250060425006758717Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein5e-94343
NC_016779:4969626:497031549703154971016702Bacillus cereus F837/76 chromosome, complete genomeMembrane Spanning Protein3e-73274
NC_012472:5015621:501562150156215016301681Bacillus cereus 03BB102, complete genomehypothetical protein8e-36150
NC_008600:5005345:500534550053455006025681Bacillus thuringiensis str. Al Hakam, complete genomehypothetical protein8e-36150
NC_003909:4951444:495719349571934957873681Bacillus cereus ATCC 10987, complete genomehypothetical protein2e-33142
NC_011658:5007691:501343850134385014106669Bacillus cereus AH187 chromosome, complete genomehypothetical protein4e-33141
NC_011969:4945441:494840749484074949075669Bacillus cereus Q1 chromosome, complete genomehypothetical protein4e-33141
NC_016771:4962795:496576149657614966429669Bacillus cereus NC7401, complete genomehypothetical protein4e-33141
NC_011725:5169135:517494051749405175608669Bacillus cereus B4264 chromosome, complete genomehypothetical protein3e-33141
NC_014171:5068500:507059450705945071274681Bacillus thuringiensis BMB171 chromosome, complete genomehypothetical protein1e-30133
NC_013791:1152500:115989211598921160569678Bacillus pseudofirmus OF4 chromosome, complete genomehypothetical protein1e-0757