Pre_GI Gene

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Host: NC_011896 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011896:2660969 Mycobacterium leprae Br4923, complete genome

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
26609692661700732hypothetical proteinBLASTP
26671482667489342hypothetical proteinBLASTP
267024726717971551hypothetical proteinBLASTP
26726452672962318hypothetical proteinBLASTP
26756922675928237hypothetical proteinBLASTP
26762442676459216antigen 84 homologQuickGO ontologyBLASTP
267718826786841497putative trehalose-phosphate synthaseQuickGO ontologyBLASTP