Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:2010140 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
201014020141173978phophoribosylformylglycinamidine synthaseQuickGO ontologyBLASTP
20142122014970759putative hydroxyacylglutathione hydrolaseQuickGO ontologyBLASTP
201999120214451455hypothetical inner membrane proteinQuickGO ontologyBLASTP
202153120225321002hypothetical proteinBLASTP
20226842023439756hypothetical outer membrane proteinQuickGO ontologyBLASTP
20234582023676219hypothetical proteinBLASTP
20238212024165345hypothetical inner membrane proteinQuickGO ontologyBLASTP
20241652024857693hypothetical inner membrane proteinQuickGO ontologyBLASTP
202492420261441221arginine biosynthesis bifunctional proteinQuickGO ontologyBLASTP
202629120276131323hypothetical inner membrane proteinQuickGO ontologyBLASTP
202780220291931392ATP-dependent DNA helicaseQuickGO ontologyBLASTP