Pre_GI Gene

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Host: NC_008600 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008600:1042477 Bacillus thuringiensis str. Al Hakam, complete genome

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Produces insect toxin. This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
10424771043469993glyoxalase family proteinQuickGO ontologyBLASTP
104367510448201146possible response regulator aspartate phosphataseQuickGO ontologyBLASTP
10448201045065246hypothetical proteinBLASTP
10453011046176876lipase alphabeta hydrolase fold familyQuickGO ontologyBLASTP
10465931047483891hypothetical proteinBLASTP
10483891048949561glycerol uptake operon antiterminator regulatory proteinQuickGO ontologyBLASTP
10491631049999837glycerol uptake facilitator proteinQuickGO ontologyBLASTP
105001310515031491glycerol kinaseQuickGO ontologyBLASTP
105159810533191722glycerol-3-phosphate dehydrogenaseQuickGO ontologyBLASTP
10540911054513423hypothetical proteinBLASTP
10547731055138366hypothetical proteinBLASTP
10554621055995534RNA polymerase sigma-70 factor ECF subfamilyQuickGO ontologyBLASTP
105641510576651251cell division protein FtsWRodASpoVE familyQuickGO ontologyBLASTP
10577231058208486transcriptional regulator MarR familyQuickGO ontologyBLASTP
10586121058827216hypothetical protein
105902010604111392major facilitator family transporter possible metal-tetracyclineH antiporterQuickGO ontologyBLASTP
106043410618851452permease general substrate transporterQuickGO ontologyBLASTP