NC_004368:726385 Streptococcus agalactiae NEM316, complete genome
Host Lineage: Streptococcus agalactiae; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria
General Information: This strain is a serotype III strain isolated from a case of fatal septicemia. Type III is responsible for 80% of neonatal GBS (group B streptococcal) meningitis. Causes meningitis and sepsis in newborns.Streptococci are Gram-positive, nonmotile, nonsporeforming, catalase-negative cocci that occur in pairs or chains. Members of this genus vary widely in pathogenic potential. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This organism is the leading cause of meningitis and sepsis in newborns. Additionally this organism is the cause of serious infections in immunocompromised adults. Able to asymptomatically colonize human skin and mucous membranes. This organism is also implicated in cases of mastitis in cows.