Pre_GI Gene

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Host: NC_017062 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017062:33268 Rickettsia typhi str. B9991CWPP chromosome, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. This organism causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. R. prowazekii, and genomic comparisons demonstrate colinearity and similarity to the genome of that organism except for two independent inversions near the origin and terminus. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
33268359282661VirB6-like protein of the type IV secretion systemQuickGO ontologyBLASTP
36090390052916VirB6-like protein of the type IV secretion systemQuickGO ontologyBLASTP
39009410332025VirB6-like protein of the type IV secretion systemQuickGO ontologyBLASTP
41020443943375VirB6-like protein of the type IV secretion systemQuickGO ontologyBLASTP
44513469302418type IV secretion system ATPase VirB4QuickGO ontologyBLASTP
4710347390288type IV secretion system protein VirB3QuickGO ontologyBLASTP
4806548709645GTP-binding protein YsxCQuickGO ontologyBLASTP
491754941123750S ribosomal protein L31QuickGO ontologyBLASTP
494084970129450S ribosomal protein L28QuickGO ontologyBLASTP
5098451235252hypothetical proteinBLASTP
5123751995759ribonucleotide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
5200152780780ABC transporter permeaseQuickGO ontologyBLASTP
52937541451209alanine racemaseQuickGO ontologyBLASTP