Pre_GI Gene

Some Help

Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:2161696 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
216062021616991080histidinol-phosphate aminotransferaseQuickGO ontologyBLASTP
216169621627631068histidinol-phosphataseimidazoleglycerol- phosphate dehydrataseQuickGO ontologyBLASTP
21627632163353591imidazole glycerol phosphate synthase glutamine amidotransferase subunitQuickGO ontologyBLASTP
21633532164090738phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomeraseQuickGO ontologyBLASTP
21640722164848777imidazoleglycerol phosphate synthase cyclase subunitQuickGO ontologyBLASTP
21648422165453612histidine biosynthesis bifunctional protein hisIEQuickGO ontologyBLASTP
21655342166517984chain length determinant proteinQuickGO ontologyBLASTP
216666021678261167udp-glucose 6-dehydrogenaseQuickGO ontologyBLASTP
2168063216946914076-phosphogluconate dehydrogenase decarboxylatingQuickGO ontologyBLASTP
216963321710631431undecaprenyl-phosphate galactose phosphotransferaseQuickGO ontologyBLASTP
217114221725781437phosphomannomutaseQuickGO ontologyBLASTP
217258621740071422mannose-1-phosphate guanylyltransferasemannose-6-phosphate isomeraseQuickGO ontologyBLASTP
217402221751791158glycosyl transferase group 1QuickGO ontologyBLASTP
217516621761761011second mannosyl transferaseQuickGO ontologyBLASTP
217617621773751200O-antigen polymeraseQuickGO ontology
217746921785121044rhamnosyl transferaseQuickGO ontologyBLASTP
21785142179128615hypothetical proteinBLASTP
21791752180137963glycosyl transferase group 2 family proteinQuickGO ontologyBLASTP
218013021814701341hypothetical proteinBLASTP
21814702182351882CDP-abequose synthaseQuickGO ontologyBLASTP
218236521836781314lipopolysaccharide biosynthesis protein RfbHQuickGO ontologyBLASTP
218370521847841080CDP-glucose 46-dehydrataseQuickGO ontologyBLASTP
21847892185562774glucose-1-phosphate cytidylyltransferaseQuickGO ontologyBLASTP
21855782186552975BLASTP
21865582187106549dTDP-4-dehydrorhamnose 35-epimeraseQuickGO ontologyBLASTP
21871102187994885glucose-1-phosphate thymidylyltransferaseQuickGO ontologyBLASTP
21880362188935900dTDP-4-dehydrorhamnose reductaseQuickGO ontologyBLASTP
218893521900201086dTDP-glucose 46-dehydrataseQuickGO ontologyBLASTP
21903972191290894regulatory protein GalFQuickGO ontologyBLASTP
219146821928711404colanic acid biosynthesis protein WcaMQuickGO ontologyBLASTP
219288221941021221putative colanic acid biosynthesis glycosyltransferase WcaLQuickGO ontologyBLASTP
219409921953791281colanic acid biosynthesis protein WcaKQuickGO ontologyBLASTP
219540121969331533lipopolysaccharide biosynthesis protein WzxCQuickGO ontologyBLASTP
219698121983751395undecaprenyl-phosphate glucose phosphotransferaseQuickGO ontologyBLASTP