Pre_GI Gene

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Host: NC_003116 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003116:988000 Neisseria meningitidis Z2491, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: This is a serogroup A strain isolated in Gambia in 1983. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
988026988286261hypothetical proteinBLASTP
988319988756438hypothetical proteinBLASTP
988770989180411DNA-binding proteinQuickGO ontologyBLASTP
989297989689393DNA-binding proteinQuickGO ontologyBLASTP
989750989977228hypothetical proteinBLASTP
989952990455504hypothetical proteinBLASTP
990756991595840heat shock protein HtpXQuickGO ontologyBLASTP
991810992457648adenylate kinaseQuickGO ontologyBLASTP
992983993723741orotidine 5-phosphate decarboxylaseQuickGO ontologyBLASTP
993778994749972DP-heptose synthetaseQuickGO ontologyBLASTP
9947869960211236modification methylaseQuickGO ontologyBLASTP
9960239971411119type II restriction endonucleaseQuickGO ontologyBLASTP
9971829981861005ADP-L-glycero-D-mannoheptose epimeraseQuickGO ontologyBLASTP
9982599998031545type I restriction-modification system proteinQuickGO ontologyBLASTP
99980010008101011DNA-binding proteinQuickGO ontologyBLASTP
100541810076972280ATP-dependent protease ATP-binding proteinQuickGO ontologyBLASTP
10077011008012312hypothetical proteinBLASTP
10082701008473204transcriptional regulatorQuickGO ontologyBLASTP
100877110101021332hypothetical proteinBLASTP