Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_003116: Neisseria meningitidis Z2491, complete genome

NCBI: NC_003116

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: This is a serogroup A strain isolated in Gambia in 1983. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
193576*12141127836Island text2.057241.426645.1678Neighbours35BLASTN+93576.gbk
2291661*31692925269Island text2.6341539.410730.3935Neighbours24BLASTN291661.gbk
365887968269623818Island text1.5594231.863127.8214Neighbours24BLASTN658879.gbk
475566677455118886Island text1.8362428.649924.8751NeighboursBLASTN+IslandViewer 755666.gbk
5867943*89021922277Island text1.5736830.602547.8986Neighbours35BLASTN+867943.gbk
6988000101010222103Island text1.5549931.675641.8748Neighbours35BLASTN988000.gbk
71018813*104163622824Island text2.1450835.377122.7284Neighbours35BLASTN1018813.gbk
81488576*150859920024Island text1.5946129.015726.661Neighbours35BLASTN+1488576.gbk
91518110*154147823369Island text1.7638732.214517.874Neighbours35BLASTN+IslandViewer 1518110.gbk
101734000175259918600Island text1.5146330.378630.0361Neighbours24BLASTN+1734000.gbk
112063500*208368920190Island text1.5975129.352229.8098Neighbours35BLASTN+IslandViewer 2063500.gbk