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Query: NC_017517:1807072:1836053 Neisseria meningitidis M01-240355 chromosome, complete genome

Start: 1836053, End: 1836631, Length: 579

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017501:543000:572788572788573366579Neisseria meningitidis 8013, complete genomehypothetical protein1e-109395
NC_009655:866281:891815891815892381567Actinobacillus succinogenes 130Z chromosome, complete genomehypothetical protein8e-49192
NC_009053:1668500:168087716808771681446570Actinobacillus pleuropneumoniae L20, complete genomehypothetical protein1e-47189
NC_006300:600516:619338619338619634297Mannheimia succiniciproducens MBEL55E, complete genomehypothetical protein4e-1374.7