Some Help

Query: NC_011896:3252925:3266994 Mycobacterium leprae Br4923, complete genome

Start: 3266994, End: 3267356, Length: 363

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia

SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:3253057:326712632671263267488363Mycobacterium leprae TN, complete genomeribonuclease P2e-55213
NC_015125:1597600:160489216048921605230339Microbacterium testaceum StLB037, complete genomeRNase P protein component2e-0651.2
NC_011886:4376261:439465443946544395064411Arthrobacter chlorophenolicus A6, complete genomeribonuclease P protein component1e-0548.9