Pre_GI: BLASTP Hits

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Query: NC_003155:5163382:5169189 Streptomyces avermitilis MA-4680, complete genome

Start: 5169189, End: 5170106, Length: 918

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016111:613729:620521620521621390870Streptomyces cattleya NRRL 8057, complete genomebifunctional DNA primase/polymerase5e-1582
NC_013929:5952380:595784059578405958745906Streptomyces scabiei 87.22 chromosome, complete genomehypothetical protein5e-1478.6
NC_010572:3363830:340155534015553402439885Streptomyces griseus subsp. griseus NBRC 13350, complete genomehypothetical protein4e-1272
NC_010617:988758:100387710038771004782906Kocuria rhizophila DC2201, complete genomehypothetical protein1e-1170.9
NC_012803:3691:296482964830592945Micrococcus luteus NCTC 2665, complete genomehypothetical protein3e-1066.2
NC_014815:3272791:329106232910623291961900Micromonospora sp. L5 chromosome, complete genomebifunctional DNA primase/polymerase4e-0962.4
NC_017030:8599515:8615278861527886180072730Corallococcus coralloides DSM 2259 chromosome, complete genomeBifunctional DNA Primase/polymerase7e-0961.6
NC_019673:1988853:202206520220652022901837Saccharothrix espanaensis DSM 44229 complete genomehypothetical protein9e-0961.2
NC_013729:2287884:229122822912282292154927Kribbella flavida DSM 17836, complete genomeBifunctional DNA primase/polymerase1e-0757.4
NC_010511:1273610:129396712939671294836870Methylobacterium sp. 4-46 chromosome, complete genomebifunctional DNA primase/polymerase2e-0756.6
NC_009142:7820251:7835759783575978367721014Saccharopolyspora erythraea NRRL 2338, complete genomehypothetical protein6e-0755.1
NC_017186:361444:373883373883374839957Amycolatopsis mediterranei S699 chromosome, complete genomehypothetical protein9e-0754.7
NC_015312:1191633:119453211945321195479948Pseudonocardia dioxanivorans CB1190 chromosome, complete genomeBifunctional DNA primase/polymerase1e-0653.9
NC_020126:2381380:2397905239790524004542550Myxococcus stipitatus DSM 14675, complete genomeBifunctional DNA Primase/polymerase1e-0653.9
NC_008060:476861:4895804895804918202241Burkholderia cenocepacia AU 1054 chromosome 1, complete sequencePhage-plasmid primase P4-like4e-0652.4
NC_008542:1021848:1034227103422710364672241Burkholderia cenocepacia HI2424 chromosome 1, complete sequencephage/plasmid primase, P4 family4e-0652.4
NC_008022:771767:780337780337781149813Streptococcus pyogenes MGAS10270, complete genomephage protein6e-0652
NC_008024:548165:555431555431556243813Streptococcus pyogenes MGAS10750, complete genomephage protein6e-0652
NC_008021:531730:538996538996539808813Streptococcus pyogenes MGAS9429, complete genomephage protein6e-0652