Query: NC_018665:650847 Exiguobacterium antarcticum B7 chromosome, complete genome
Lineage: Exiguobacterium antarcticum; Exiguobacterium; Bacillales Family XII; Bacillales; Firmicutes; Bacteria
General Information: Exiguobacterium antarcticum (strain B7) is a psychotropic Gram-positive bacterium isolated from microbial biofilm at Ginger Lake, located on King George Island, Antarctic peninsula.
Subject: NC_007797:914500 Anaplasma phagocytophilum HZ, complete genome
Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.