Pre_GI Gene

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Host: NC_007797 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007797:914500 Anaplasma phagocytophilum HZ, complete genome

Host Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria

General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
9149189162491332phage major capsid protein HK97 familyQuickGO ontologyBLASTP
916763916870108hypothetical protein
91763292034927182-oxoglutarate dehydrogenase E1 componentQuickGO ontologyBLASTP
920359920484126hypothetical protein
92082692089772tRNA-GlyQuickGO ontology
921418921546129hypothetical protein
9215309228281299adenylosuccinate lyaseQuickGO ontologyBLASTP
923159923371213hypothetical proteinBLASTP
92349992359799hypothetical proteinBLASTP
923795924043249hypothetical protein
92414292424099hypothetical protein
92436892446699hypothetical proteinBLASTP
924565924675111hypothetical protein
9246849278273144hypothetical proteinBLASTP
929043929180138hypothetical protein
930013930738726biotin--acetyl-CoA-carboxylase ligaseQuickGO ontologyBLASTP
93148893158093hypothetical protein
9327959340541260hypothetical protein