Query: NC_017512:2087098 Neisseria meningitidis WUE 2594, complete genome
Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.
Subject: NC_009439:4267356 Pseudomonas mendocina ymp, complete genome
Lineage: Pseudomonas mendocina; Pseudomonas; Pseudomonadaceae; Pseudomonadales; Proteobacteria; Bacteria
General Information: Soil and subsurface bacterium. Strain ymp was isolated as part of the Yucca Mountain Project from sediment in a surface holding pond of a drilling operation at the Nevada Test Site, NV, USA (the proposed site of the high-level nuclear repository). Bacteria belonging to the Pseudomonas group are common inhabitants of soil and water and can also be found on the surfaces of plants and animals. Pseudomonas bacteria are found in nature in a biofilm or in planktonic form. Pseudomonas bacteria are renowned for their metabolic versatility as they can grow under a variety of growth conditions and do not need any organic growth factors. Pseudomonas mendocina is a pentachlorophenol (PCP)-degrading bacterium was isolated from PCP-contaminated soil. It is able to act as a bioremediation agent without the accumulation of inhibitory toxic compounds.