Pre_GI: SWBIT SVG BLASTP

Query: NC_017505:1338661 Neisseria meningitidis alpha710 chromosome, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Subject: NC_015312:1 Pseudonocardia dioxanivorans CB1190 chromosome, complete genome

Lineage: Pseudonocardia dioxanivorans; Pseudonocardia; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Country: USA; Environment: Sludge, Fresh water; Isolation: Industrial sludge contaminated; Temp: Mesophile; Temp: 30C. Pseudonocardia members are abundant in diverse environments, and are known to degrade a variety of pollutants. These bacteria are also important in biocatalysis applications and in the production of antibiotics. Pseudonocardia dioxanivorans was first isolated from 1,4-dioxane containing sludge. This organism is able to grow using 1,4-dioxane, a toxic compound used as an industrial solvent, as the sole carbon source.