Pre_GI: SWBIT SVG BLASTP

Query: NC_016933:400790 Francisella tularensis TIGB03 chromosome, complete genome

Lineage: Francisella tularensis; Francisella; Francisellaceae; Thiotrichales; Proteobacteria; Bacteria

General Information: This organism was first identified by Edward Francis as the causative agent of a plague-like illness that affected squirrels in Tulare county in California in the early part of the 20th century. The organism now bears his name. The disease, which has been noted throughout recorded history, can be transmitted to humans by infected ticks or deerflies, infected meat, or by aerosol, and thus is a potential bioterrorism agent. This organism has a high infectivity rate, and can invade phagocytic and nonphagocytic cells, multiplying rapidly. Once within a macrophage, the organism can escape the phagosome and live in the cytosol. It is an aquatic organism, and can be found living inside protozoans, similar to what is observed with Legionella.

Subject: NC_014313:2059933 Hyphomicrobium denitrificans ATCC 51888 chromosome, complete

Lineage: Hyphomicrobium denitrificans; Hyphomicrobium; Hyphomicrobiaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Environment: Fresh water; Temp: Mesophile. An aerobic, motile Gram-negative bacterium. Hyphomicrobium denitrificans has a biphasic life style, which consists of a motile phase of flagellated swarmer cells, and a cessile phase in which a long prosthecate is produced at one end of the bacteria through which budding cells emerge. Newly budded cells in turn produce flagella and go through a motile phase and the cycle continues. These organisms can colonize the surfaces of marine environments which enables additional species to colonize at later stages. This organism is also able to utilize methanol as a sole source of energy.