Pre_GI: SWBIT SVG BLASTP

Query: NC_015744:668665 Chlamydia trachomatis L2c chromosome, complete genome

Lineage: Chlamydia trachomatis; Chlamydia; Chlamydiaceae; Chlamydiales; Chlamydiae; Bacteria

General Information: This strain was isolated from a man with severe proctitis. This species causes infection that leads to blindness and sexually transmitted diseases in humans. There are 15 serovariants that preferentially cause disease in either the eye or the urogenital tract. The trachoma (infection of the mucous membrane of the eyelids) biovars are noninvasive and can cause blinding trachoma (variants A, B, Ba, and C), or sexually transmitted diseases (variants, D, E, F, G, H, I, J, and K). The lymphogranuloma venereum biovars (variants L1, L2, and L3) can cross the epithelial cells of mucous membranes and then travel through the lymphatic system where they multiply within mononuclear phagocytes found within the lymph nodes. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. This species causes infection that leads to blindness and sexually transmitted diseases in humans.

Subject: NC_009480:2932108 Clavibacter michiganensis subsp. michiganensis NCPPB 382, complete

Lineage: Clavibacter michiganensis; Clavibacter; Microbacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Phytopathogen that causes bacterial wilt and canker of tomato (Lycopersicon esculentum). This is considered to be the most important bacterial disease of tomato causing substantial economic losses worldwide. Bacteria enter the plant by wounds on root or stem and then find their way into the xylem allowing a massive systemic colonization. The first stage of the disease is characterized by unilateral wilting of leaves. Wilting then spreads to all leaves, canker lesions develop on the stem and the plant dies. If infection occurs at a late stage of plant development, plants can survive and yield fruit that may have spots, so called bird's eyes. Often the seeds will be infected and this has been the major source for outbreaks of Clavibacter michiganensis subsp. michiganensis infections in agriculture. Members of the Clavibacter genus are known to produce antimicrobial compounds.