Query: NC_014935:31020 Nitratifractor saLSUginis DSM 16511 chromosome, complete genome
Lineage: Nitratifractor salsuginis; Nitratifractor; ; Campylobacterales; Proteobacteria; Bacteria
General Information: Country: Japan; Isolation: Deep-sea hydrothermal vent chimney; Temp: Mesophile; Temp: 37C. This organism was isolated from the Iheya North hydrothermal field inthe Mid-Okinawa Trough, Japan. It is a strict chemolithoautotroph, growing byrespiratory nitrate reduction with H2, forming N2 as a metabolic product.
Subject: NC_007797:914500 Anaplasma phagocytophilum HZ, complete genome
Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.