Query: NC_014150:2201251 Brachyspira murdochii DSM 12563 chromosome, complete genome
Lineage: Brachyspira murdochii; Brachyspira; Brachyspiraceae; Spirochaetales; Spirochaetes; Bacteria
General Information: Environment: Host, Intestinal microflora; Isolation: intestinal contents of healthy swine; Temp: Mesophile. Formerly Serpulina murdochii, this organism is part of the normal flora of the pig gastrointestinal tract.
Subject: NC_000963:141500 Rickettsia prowazekii str. Madrid E, complete genome
Lineage: Rickettsia prowazekii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This strain is an egg-passaged attentuated avirulent strain that has been used as a live vaccine and was originally isolated from a typhus patient in Madrid. This species is the causal agent of typhus. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host.