Query: NC_014034:3570034 Rhodobacter capsulatus SB1003 chromosome, complete genome Lineage: Rhodobacter capsulatus; Rhodobacter; Rhodobacteraceae; Rhodobacterales; Proteobacteria; Bacteria General Information: This strain is a derivative strain isolated in the laboratory of Barry Marrs from the classical progenitor strain B10. It is rifampicin-resistant, produces GTA, and is capable of growing under high illumination (resistant to photooxidative killing). Bacteria belonging to the Rhodobacter group are metabolically versatile as they are able to use photosynthesis and usually can grow under both anaerobic and aerobic conditions. This organism is a facultatively phototrophic purple non-sulfur bacterium and the type species of the Rhodobacter group. The colony's color depends largely on the amount of oxygen present in its environment. While it is able to produce cellular energy in a number of different ways, it can rely on anoxygenic photosynthesis under anaerobic conditions in the presence of light. Some strains produce the Gene Transfer Element (GTA), a pro-phage particle capable of transferring genetic material between strains.
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General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.