Query: NC_013861:1498212 Legionella longbeachae NSW150, complete genome
Lineage: Legionella longbeachae; Legionella; Legionellaceae; Legionellales; Proteobacteria; Bacteria
General Information: Legionella longbeachae is the predominant cause of Legionnaires' disease in Australia, but is an uncommon pathogen in other parts of the world. Legionella longbeachae infection has been associated with exposure to potting soil in Australia, the USA, Japan and the Netherlands. L. longbeachae is found predominantly in moist potting soil.
Subject: NC_004917:946550 Helicobacter hepaticus ATCC 51449, complete genome
Lineage: Helicobacter hepaticus; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria
General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.