Query: NC_013740:571879 Acidaminococcus fermentans DSM 20731, complete genome
Lineage: Acidaminococcus fermentans; Acidaminococcus; Acidaminococcaceae; Selenomonadales; Firmicutes; Bacteria
General Information: Isolation: Pig gut; Temp: Mesophile; Temp: 37C; Habitat: Host, Intestinal tract. Anaerobic Gram-negative bacterium . Acidaminococcus fermentans was isolated from a pig gut. This organism can utilize amino acids as the sole source of energy for growth.
Subject: NC_007797:914500 Anaplasma phagocytophilum HZ, complete genome
Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.