Pre_GI: SWBIT SVG BLASTP

Query: NC_013169:1545890 Kytococcus sedentarius DSM 20547, complete genome

Lineage: Kytococcus sedentarius; Kytococcus; Dermacoccaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Country: USA; Temp: Mesophile; Temp: 28 - 36C; Habitat: Marine, Skin microflora. Strain DSM 20547, the type strain, is a free-living, nonmotile, Gram-positive bacterium, originally isolated from a marine environment in about 1944. It grows as spherical/coccoid and occurs predominantly in tetrads which can be arranged in cubical packets. It is non-encapsulated and does not form endospores, is strictly aerobic and chemoorganotrophic, requires methionine and other amino acids for growth, and grows well in NaCl at concentrations up to 10% (w/v). This organism is a normal commensal of human skin, however has been implicated in pitted keratolysis, pneumonia, and other opportunistic infections.

Subject: NC_004551:100840 Tropheryma whipplei TW08/27, complete genome

Lineage: Tropheryma whipplei; Tropheryma; Cellulomonadaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from the cerebrospinal fluid a woman who had suffered severe weight loss in Germany. The patient had been treated with antibiotics followed by a year of no treatment prior to the sample being taken. This bacterium is the causative agent of Whipple's disease. Whipple did not associate the disease with any bacterial agent, and it was only in 1961 when bacteria were detected in electron microphotographs of affected tissues that the connection was made. The bacterium cannot be cultured apart from its eukaryotic host, and it grows very slowly (reported duplication time 4-17 days).