Query: NC_012815:1465670 Bifidobacterium animalis subsp. lactis DSM 10140, complete genome Lineage: Bifidobacterium animalis; Bifidobacterium; Bifidobacteriaceae; Bifidobacteriales; Actinobacteria; Bacteria General Information: Bifidobacterium animalis subsp. lactis (strain DSM 10140 / JCM 10602 / LMG 18314) is an anaerobic Gram-positive lactic acid bacterium commonly found in the guts of healthy humans and has been identified in the infant gut biota, particularly in ileal, fecal, and mucosal samples. Some strains of B. animalis subsp. lactis are able to survive in the GIT, to adhere to human epithelial cells in vitro, to modify fecal flora, to modulate the host immune response, or to prevent microbial gastroenteritis and colitis.
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General Information: This strain was isolated from a sample of coastal sea water near a French Antarctic station. This organism is adapted to growth at low temperatures and reactive oxygen species by a number of putative dioxygenases and fatty acid desaturases amongst other proteins. The organism can grow optimally in salt concentrations of 1.5 to 3.5% NaCl.The genome consists of 2 chromosomes, one of which may replicate unidirectionally. Some interesting features of this genome include the lack of the nucleoid-associated gene hns, a lack of genes involved in molybdopterin metabolism, a lack of the cAMP-CAP complex, and a lack of the PEP-dependent PTS system.