Query: NC_012803:2195808 Micrococcus luteus NCTC 2665, complete genome
Lineage: Micrococcus luteus; Micrococcus; Micrococcaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Temp: Mesophile; Habitat: Soil. Micrococcus luteus NCTC 2665 has potential in bioremediation due to its ability to sequester metals (i.e. gold and strontium), and it is being used for gold concentration from low-abundance ores. Micrococcus luteus was originally isolated by Alexander Fleming in 1929 as Micrococcus lysodeikticus. This organism can be found in many environments including soil, water, animals, and dairy products. Micrococcus luteus is able to survive in the environment for long periods and has been isolated from inclusions in amber.
Subject: NC_006085:925604 Propionibacterium acnes KPA171202, complete genome
Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.