Pre_GI Gene

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Host: NC_006085 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006085:925604 Propionibacterium acnes KPA171202, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
9256049272951692transfer protein homolog TraAQuickGO ontologyBLASTP
927480927977498conserved protein putative DNA processing Smf-family proteinQuickGO ontologyBLASTP
9282669298731608hypothetical proteinBLASTP
9298749315621689putative ATP-dependent DNA helicase PcrAQuickGO ontologyBLASTP
932989933183195hypothetical protein
933340933630291hypothetical protein
933712933912201hypothetical protein
934056934355300hypothetical protein
935053935337285hypothetical protein putative transposaseQuickGO ontologyBLASTP
935472935996525putative transposase subunitQuickGO ontologyBLASTP
9361989388102613hypothetical protein putative lanthionine biosynthesis proteinQuickGO ontologyBLASTP
938791939744954hypothetical protein putative lanthionine biosynthesis proteinQuickGO ontologyBLASTP
9397419408231083hypothetical protein
9408239421421320conserved protein DUF181QuickGO ontologyBLASTP
942173942763591hypothetical protein
9427879443551569hypothetical protein
944352945068717hypothetical protein
945258945503246hypothetical protein
946094946366273hypothetical protein
946715946999285hypothetical protein
947043947327285hypothetical proteinBLASTP
947633948139507transcriptional regulatorQuickGO ontologyBLASTP
948169948480312conserved protein putative Y4OV fragmentQuickGO ontologyBLASTP
948499948768270conserved protein putative Y4OU fragmentQuickGO ontologyBLASTP
948738948926189conserved protein putative Y4OU fragmentQuickGO ontologyBLASTP
949031949723693conserved protein putative Y4OU fragmentQuickGO ontologyBLASTP
9498489512361389putative GntR-family regulatory proteinQuickGO ontologyBLASTP
951486951725240putative transposase subunitQuickGO ontologyBLASTP
9522579545962340UvrA-like ABC transporterQuickGO ontologyBLASTP
954589955017429transcriptional repressor MarR familyQuickGO ontologyBLASTP
955443956387945transcriptional regulator SorC familyQuickGO ontologyBLASTP
956567957559993putative phosphotriesteraseQuickGO ontologyBLASTP
957565958218654hexulose phosphate synthaseQuickGO ontologyBLASTP
958215959102888hexulose-6-phosphate isomeraseQuickGO ontologyBLASTP