Query: NC_012785:2010668 Kosmotoga olearia TBF 19.5.1, complete genome Lineage: Kosmotoga olearia; Kosmotoga; Thermotogaceae; Thermotogales; Thermotogae; Bacteria General Information: Gram-negative bacterium Kosmotoga olearia TBF 19.5.1 was isolated from an oil deposit. Broad temperature growth range. This organism is a member of the Thermotogales and has the characteristic morphology of one or more cells contained in a sheath-like envelope which extends beyond the cell wall. Preliminary sequencing of Thermotogales genomes has identified extensive horizontal gene transfer between these organisms and the Archaea.
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General Information: Citrobacter rodentium is the causative agent of transmissible murine colonic hyperplasia in mice. This disease is characterized by a hyperproliferation of the epithelial cells in the colon similar to that found in humans suffering from idiopathic inflammatory bowel disease. In addition this organism contains virulence factors similar to those found in enterohemorrhagic Escherichia coli and enteropathogenic E. coli. C. rodentium are being used as models for studying mucosal response to infection, colon tumor production, and virulence associated with pathogenic E. coli.