Query: NC_011896:3252925 Mycobacterium leprae Br4923, complete genome Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.
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General Information: Oil pollution has become a global issue because of its severe ecological impact and destruction. Bioremediation is proved to be an effective process to restore the oil polluted environments. Bacteria from oil contaminated environment always have the abilities for degradation of hydrocarbons and are thought to be useful in bioremediation of oil pollution. Amycolicicoccus subflavus DQS-9A1T, an actinomycete, is a type strain of newly published novel species in the novel genus Amycolicicoccus, isolated from the crude oil-polluted saline soil in China. The complete genome sequence of Amycolicicoccus subflavus DQS-9A1 will provide new strategies for bioremediation of oil contaminated environment.