Query: NC_011837:830436 Clostridium kluyveri NBRC 12016, complete genome Lineage: Clostridium kluyveri; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria General Information: Involved in production of caproic acid in co-culture with a methanogen. Clostridium kluyveri was enriched from mud in a co-culture with Methanobacterium omelianskii. When grown on ethanol C. kluyveri produce caproic acid in addition to acetic acid. This organism is able to grow anaerobically on ethanol and acetate as sole energy sources.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.