Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:1888950 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
188895018904191470hypothetical proteinBLASTP
189355518947631209putative replication initiation factorQuickGO ontologyBLASTP
18947841895095312hypothetical proteinBLASTP
18950991895299201hypothetical proteinBLASTP
18955371895767231hypothetical proteinBLASTP
18957961896098303putative integral membrane proteinQuickGO ontologyBLASTP
189654518980501506TspB proteinQuickGO ontologyBLASTP
18983531898637285Putative integral membrane proteinQuickGO ontologyBLASTP
189863818998251188hypothetical proteinBLASTP
19000401900996957putative invertasetransposaseQuickGO ontologyBLASTP
19020801902325246hypothetical proteinBLASTP
19024281902865438conserved hypothetical inner membrane proteinQuickGO ontologyBLASTP
19028621903353492hypothetical proteinBLASTP
19037031904191489dihydrofolate reductaseQuickGO ontologyBLASTP
190425919053141056phospho-2-dehydr-3-deoxyheptonate aldolaseQuickGO ontologyBLASTP
19053681905661294hypothetical proteinBLASTP
1905779190587193hypothetical protein
19059601906238279pseudogene outer membrane proteinQuickGO ontology
19064951906941447hypothetical protein
19070661907530465putative DNA transport competence proteinQuickGO ontologyBLASTP
190756619076821175S ribosomal RNAQuickGO ontologyBLASTP