Query: NC_011761:1357799 Acidithiobacillus ferrooxidans ATCC 23270 chromosome, complete
Lineage: Acidithiobacillus ferrooxidans; Acidithiobacillus; Acidithiobacillaceae; Acidithiobacillales; Proteobacteria; Bacteria
General Information: This organism was isolated from bituminous coal mine effluent. Acidophilic iron-oxidizing bacterium. Acidithiobacillus ferrooxidans, formerly Thiobacillus ferrooxidans, is an acidophilic iron-oxidizing bacterium that is able to grow at a pH range of 1.3 to 4.0. This organism is often identified in acid mine drainage and as a member of microbial consortia involved in bioleaching. Acidithiobacillus ferrooxidans has been identified as the dominant microorganism in percolation and continuous flow mineral leaching bioreactors.
Subject: NC_009651:19909 Klebsiella pneumoniae subsp. pneumoniae MGH 78578 plasmid pKPN5,
Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.