Pre_GI Gene

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Host: NC_009651 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009651:19909 Klebsiella pneumoniae subsp. pneumoniae MGH 78578 plasmid pKPN5,

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
19909210961188putative transposaseQuickGO ontologyBLASTP
2161321777165hypothetical proteinBLASTP
2175822459702putative resolvaseQuickGO ontologyBLASTP
2312123837717hypothetical proteinBLASTP
2451924767249putative adenosylmethionine-8-amino-7-oxononanoate aminotransferaseQuickGO ontologyBLASTP
2476425315552hypothetical proteinBLASTP
2544826200753hypothetical proteinBLASTP
2625326909657glutamine ABC transporter permease proteinQuickGO ontologyBLASTP
2690627136231hypothetical protein
2729028105816aminoglycoside 3-phosphotransferase APH IQuickGO ontologyBLASTP
2824528961717putative transposaseQuickGO ontologyBLASTP
2894029788849replication initiator proteinQuickGO ontologyBLASTP
3042930950522hypothetical protein
3100831799792putative dihydrofolate reductaseQuickGO ontologyBLASTP
32129336701542hypothetical proteinBLASTP
3407534914840dihydropteroate synthaseQuickGO ontologyBLASTP
3490835255348QacEdelta1 small multidrug resistance proteinQuickGO ontologyBLASTP
35447367541308chloramphenicol resistance proteinQuickGO ontologyBLASTP
3699637334339integraseQuickGO ontologyBLASTP
3766738416750aminoglycoside adenylyltransferaseQuickGO ontologyBLASTP
38346393591014integraseQuickGO ontologyBLASTP
3967540391717transposaseQuickGO ontologyBLASTP
4062541206582hypothetical proteinBLASTP
41509428551347hypothetical proteinBLASTP
4290643328423hypothetical protein