Pre_GI: SWBIT SVG BLASTP

Query: NC_011601:2998326 Escherichia coli O127:H6 str. E2348/69 chromosome, complete genome

Lineage: Escherichia coli; Escherichia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Enteropathogenic Escherichia coli (EPEC) is an important cause of fatal infant diarrhea. EPEC induces diarrhea by attaching and effacing to host cells in the small intestine, inducing cytoskeletal rearrangements that result in pedastel formation, and then by introducing toxins into the host cell. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.

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BLASTP Alignment.txt

Subject: NC_008228:2068641 Pseudoalteromonas atlantica T6c, complete genome

Lineage: Pseudoalteromonas atlantica; Pseudoalteromonas; Pseudoalteromonadaceae; Alteromonadales; Proteobacteria; Bacteria

General Information: Isolated from a biofilm from San Diego Bay in California. Marine biofilm bacterium associated with shell disease in shellfish. A common marine bacterium that exists both in the water column, and in biofilms attached to surfaces. This organism produces a well characterized, commercially important agarase. Pseudoalteromonas atlantica has been isolated from lesions on crabs with shell disease. Shell disease is characterized by progressive degradation of the shell, often leading to an infection of the hemolymph (blood) and may be caused by Pseudoalteromonas, Alteromonas, Vibrio, or other marine organisms. In addition to producing extracellular enzymes which attack the shell, Pseudoalteromonas atlantica produces a the lipopolysaccharide which has been shown to be a potential virulence factor in shell disease.