Query: NC_010803:1132500 Chlorobium limicola DSM 245, complete genome Lineage: Chlorobium limicola; Chlorobium; Chlorobiaceae; Chlorobiales; Chlorobi; Bacteria General Information: Isolated from Gilroy Hot Spring. The green sulfur bacteria (GSB; Phylum Chlorobi ) are commonly found in illuminated, stratified, and anoxic aquatic environments, sediments, and other sulfide-rich environments including hot springs. This bacterium has been used to model a variety of enzyme and reaction center pathways, including ATP-citrate lyase, isocitrate dehydrogenase, and the reverse Krebs cycle used in photosynthesis. Now called the "reductive carbolic acid cycle", this was found to be the sole carbon dioxide assimilation pathway in other green sulfur bacteria since its discovery.
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General Information: This strain was isolated on Trinidad and Tobago. It is a symbiont of the nematode Heterorhabditis bacteriophora. Bioluminescent bacterium. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype. Enzymes are then released by the bacteria that result in rapid degradation of the insect body, allowing both bacteria and nematode to feed and reproduce. During this period Photorhabdus luminescens releases bacteriocidal products, including antibiotics and bacteriocins, that prevent infection of the larva by competitive microbes. The result is promotion of Photorhabdus luminescens-nematode interactions that result in continuation of the symbiotic relationship. In order to engage in a symbiotic relationship with the nematode and a pathogenic one with the insect larva, the bacterium encodes specific factors that encourage both. These include a large number of genes that code for secreted toxins and enzymes, as well as genes that encode products for the production of antibiotics and bacteriocins. Secretion of these products occurs by an array of systems including type I, type II, and type III secretion systems. The type III system is closely related to the Yersinia plasmid-encoded type III system. Genes that promote symbiotic relationships are also encoded on genomic islands on the chromosome including some that affect nematode development. Virulence genes appear to be active during exponential growth. Symbiotic genes appear to function during stationary phase (post-exponential) growth. The switch from one state to another is controlled. Photorhabdus luminescens is capable of giving off light, a complex process that requires the products of the lux operon.