Pre_GI Gene

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Host: NC_005126 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005126:274000 Photorhabdus luminescens subsp. laumondii TTO1, complete genome

Host Lineage: Photorhabdus luminescens; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated on Trinidad and Tobago. It is a symbiont of the nematode Heterorhabditis bacteriophora. Bioluminescent bacterium. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype. Enzymes are then released by the bacteria that result in rapid degradation of the insect body, allowing both bacteria and nematode to feed and reproduce. During this period Photorhabdus luminescens releases bacteriocidal products, including antibiotics and bacteriocins, that prevent infection of the larva by competitive microbes. The result is promotion of Photorhabdus luminescens-nematode interactions that result in continuation of the symbiotic relationship. In order to engage in a symbiotic relationship with the nematode and a pathogenic one with the insect larva, the bacterium encodes specific factors that encourage both. These include a large number of genes that code for secreted toxins and enzymes, as well as genes that encode products for the production of antibiotics and bacteriocins. Secretion of these products occurs by an array of systems including type I, type II, and type III secretion systems. The type III system is closely related to the Yersinia plasmid-encoded type III system. Genes that promote symbiotic relationships are also encoded on genomic islands on the chromosome including some that affect nematode development. Virulence genes appear to be active during exponential growth. Symbiotic genes appear to function during stationary phase (post-exponential) growth. The switch from one state to another is controlled. Photorhabdus luminescens is capable of giving off light, a complex process that requires the products of the lux operon.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2743512764622112ATP-dependent DNA helicaseQuickGO ontologyBLASTP
277866278471606hypothetical protein
278598279338741hypothetical proteinBLASTP
279367279948582hypothetical proteinBLASTP
280828281484657hypothetical protein
281565282284720hypothetical proteinBLASTP
2832992859292631hypothetical proteinBLASTP
2860982874231326hypothetical protein
288052288561510hypothetical protein
2884932906222130guanosine-35-bisDiphosphate 3-pyrophosphohydrolase ppGppase penta-phosphate guanosine-3-pyrophosphohydrolaseQuickGO ontologyBLASTP
290628290918291DNA-directed RNA polymerase omega subunitQuickGO ontologyBLASTP
290958291581624guanylate kinaseQuickGO ontologyBLASTP
291663291872210hypothetical protein
2938142950491236hypothetical proteinBLASTP