Pre_GI: SWBIT SVG BLASTP

Query: NC_010475:2896000 Synechococcus sp. PCC 7002, complete genome

Lineage: Synechococcus; Synechococcus; Synechococcaceae; Chroococcales; Cyanobacteria; Bacteria

General Information: The cyanobacterium Synechococcus sp. PCC 7002 (formerly known as Agmenellum quadruplicatum strain PR-6) was originally isolated in 1961 by Chase Van Baalen from an onshore, marine mud flat sample derived from fish pens on Maguyes Island, La Parguera, Puerto Rico. The organism grows in brackish (euryhaline/marine) water and is unicellular but tends to form short filaments of two to four cells during exponential growth at the temperature optimum of 38 degrees C. The strain is extremely tolerant of high light intensities and has been grown at light intensities equivalent to two suns. This unique combination of physiological and genetic properties have long made this strain an important model system to studies of the oxygenic photosynthetic apparatus, the regulation of carbon and nitrogen metabolism, and other aspects of cyanobacterial physiology and metabolism.

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Subject: NC_008767:1888950 Neisseria meningitidis FAM18, complete genome

Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.