Query: NC_009831:5107924 Shewanella sediminis HAW-EB3, complete genome
Lineage: Shewanella sediminis; Shewanella; Shewanellaceae; Alteromonadales; Proteobacteria; Bacteria
General Information: Shewanella sediminis was isolated from sediment taken at a depth of 215 meters from an unexploded-ordinance-dumping site 50 nautical miles from Halifax Harbor, Canada in the Atlantic Ocean. This organism is able to degrade hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) anaerobically at 10 degrees C. RDX is a member of a family of nitramine compounds which are used in the production of explosives. Shewanella are facultatively anaerobic, Gram-negative bacteria, motile by polar flagella, rod-like, and generally associated with aquatic or marine environments.
Subject: NC_009648:4656187 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome
Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.