Pre_GI Gene

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Host: NC_009648 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009648:4656187 Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
46552874656204918DNA-binding transcriptional regulator OxyRQuickGO ontologyBLASTP
465618746575871401soluble pyridine nucleotide transhydrogenaseQuickGO ontologyBLASTP
46577874658419633DNA-binding transcriptional repressor FabRQuickGO ontologyBLASTP
46584354658794360hypothetical proteinBLASTP
465884646599461101tRNA uracil-5--methyltransferaseQuickGO ontologyBLASTP
466031346621691857vitamin B12cobalamin outer membrane transporterQuickGO ontologyBLASTP
46621834662965783glutamate racemaseQuickGO ontologyBLASTP
4665156466523176tRNA-AlaQuickGO ontologyBLASTP
4668572466864877tRNA-AspQuickGO ontologyBLASTP
4668702466877776tRNA-TrpQuickGO ontologyBLASTP
46688864669719834transcriptional regulator HdfRQuickGO ontologyBLASTP
46698264670164339hypothetical proteinBLASTP
467018946717091521putative 2-component regulatorQuickGO ontologyBLASTP
467230346739491647acetolactate synthase 2 catalytic subunitQuickGO ontologyBLASTP
46739464674203258acetolactate synthase 2 regulatory subunitQuickGO ontologyBLASTP
46742204675149930branched-chain amino acid aminotransferaseQuickGO ontologyBLASTP
467521046770601851dihydroxy-acid dehydrataseQuickGO ontologyBLASTP